Information on How Cialis Works

Impotence treatment with prescription medicines is generally considered safe and reliable. Cialis tadalafil is among the most preferred impotence pills available on the market. It can improve erection firmness by intensifying the supply of blood to the penis. That said, an erection is a complex process involving a number of simultaneous inputs from the brain, nervous system, and penis. Cialis has a unique and target-specific action mechanism that makes it doubly effective in treating erectile dysfunction. To learn how Cialis works, you must first of all understand the entire process leading to an erection.

Blood flow and smooth muscle relaxation in the body

Our bodies consist of many smooth muscles and for the arteries to carry blood smoothly, those muscles must relax and let the arteries expand. Lack of blood flow to the penis is the most common cause of erectile dysfunction. It occurs because smooth muscles in the penis do not work properly. A vasodilatory drug like phentolamine lets the smooth muscles in the body relax, so as to increase blood flow in the arteries. But the problem with such a drug is that it acts on all smooth muscles and not on selective areas in the body. The discovery of sildenafil in the mid-1990s was a remarkable phenomenon because for the first time scientists found a drug that can selectively work on the penile smooth muscles. Tadalafil, the active ingredient in Cialis, is also similar to sildenafil and can have vasodilatory effect on the smooth muscles in the penis to increase blood flow.

Factors that inhibit blood flow to the penis

The overall action mechanism of Cialis involves dilation of blood vessels in the penis. There are several factors that may obstruct penile blood flow, leading to a weak erection. Rapid degradation of a chemical known as cGMP by a protein compound called phosphodiesterase type-5 (PDE-5) is one of the three primary reasons behind insufficient blood flow to the penis. Tadalafil can inhibit the action of PDE-5 to let cGMP build up in the chambers of the penis, so as to help expand the inner walls of the arteries in the penis. Blood flow increases as cGMP builds up, leading to stiffening of the penis in response to sexual arousal.

What happens when I take a Cialis pill?

First the active ingredient and the other ingredients in Cialis enter your bloodstream and act on PDE-5 to nullify its action on cGMP. As soon as you get sexually stimulated, your brain signals the NANC cells in the penis to produce nitric oxide. Increased production of nitric oxide helps formulate cGMP which, relaxes the smooth muscles and dilates the penile arteries. Consequently, a greater volume of blood flows to your penis, helping you to get an erection and maintain it throughout sex. Note that the role of penile valves in keeping the blood trapped inside the penis after an erection is produced is very important in helping a man sustain his erections.